sharing sensitive information, make sure youre on a federal This water contains copper ions that help increase melanin production in the body and reduce the appearance of white patches caused by vitiligo. Thus, Cu plays a role in melanogenesis however, we need to look at the role of Cu in the pathogenesis of vitiligo. Vitiligo usually develops before age 40, and people suffering with this. in biology and human physiology. Autoimmune disease; EGCG; Ginkgo biloba; Oxidative stress; Polypodium leucotomos; Vitamin D; Vitamins; Vitiligo. Therefore, we undertook a study to evaluate serum Zn and Cu levels in vitiligo. 2022 Jan 29;14(3):591. doi: 10.3390/nu14030591. However, Shameer et al. Kumar R, Parsad D. Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces. The growth of the Vitiligo Treatment market was mainly driven by the increasing RandD spending across the world. Serum copper and zinc levels in vitiligo patients. Mean serum Cu of first degree relatives was also low. Among other studies, Haider et al. You may be trying to access this site from a secured browser on the server. Materials and Methods: All cases of vitiligo attending tertiary care hospital were included in the study. A bracelet made out of pure copper can boost immunity and energy levels to a great extent. 0000000576 00000 n Copper is an important trace mineral that improves metabolic processes in the body and benefits the skin. Your email address will not be published. Currently, the autocytotoxic and the autoimmune theories are the most accredited hypothesis, since they are sustained by several important clinical and experimental evidences. But, it has been established that copper is another cofactor in melanin production, and many patients with vitiligo are found low in it. News-Medical. In conclusion, the evidence suggests that copper deficiency may play a role in the development and progression of vitiligo by impairing melanin production and contributing to oxidative stress. Clinica Chimica Acta 1972;32:207-11. https://www.pigmentinternational.com/text.asp?2021/8/1/30/313135, Pigment International | Published by Wolters Kluwer -. [12] also observed lower levels in patients than in controls but this wasnt statistically significant. Genova D, Bozhkov B, Zlatkov NB. Copper bracelets can help deal with the copper-zinc imbalance to stimulate melanin production, thereby increasing the likelihood and speed of turning the patches back into normal skin. Another study demonstrated that copper supplementation led to a significant improvement in skin pigmentation in participants with vitiligo. Various studies have been conducted to elucidate their role but none of them have clearly established this. Preliminary observations suggest that the presence of gluten in the diet may play a role in vitiligo development in some patients, but to date vitiligo-specific diets have not been studied. Parsad D, Dogra S, Kanwar AJ. National Library of Medicine In addition to this, though the Chinese meta-analysis showed lower Cu and Zn levels, the efficacy evaluation of supplemental Cu or Zn in the treatment of vitiligo was not reported in any of the 16 articles. Kumar R, Parsad D. Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces. Hence, always consult your doctor for the appropriate dosages. Gopal k, Rama Rao GR, Kumar YH, Appa Rao MV, Vasudev P, Srikant. 65 14 Parsad D, Dogra S, Kanwar AJ. J Am Acad Dermatol 2011;65:473-91. Serum copper was measured by mind-ray (automation). Analysis of tissue and serum copper in vitiligo What You Need To Know, How To Increase Melanin In Skin For Vitiligo. It appears that rhododenol, an active ingredient in the product that is also a phenol that resembles tyrosine, is responsible for inducing vitiligo in those that used the product. The purpose of this study was to evaluate the efficacy of supplemental Zn on the treatment of vitiligo. Unite For Vitiligo will not be liable for any losses, injuries, or damages arising from its display or use. Hence, the levels of these two elements are not interdependent on each other. Both genetic and environmental factors are believed to play a role in the pathogenesis of the disease [1, 2]. Haider N, Islam M, Al Maruf A, Shohag M, Ali R, Rahman G. Helmy M, Gayyar E, Hawas S. Role of oxidative stress in the pathogenesis of vitiligo. Vegetarians constituted 27 out of 100 cases (27%), whereas 73 (73%) were non-vegetarians. In: valia RG, Valia AR, eds. 2023 Jan 14;12(2):673. doi: 10.3390/jcm12020673. disease, Addison disease, copper deficiency, parasitosis, and diabetes mellitus .18,19 Besides it s physical manifestations, vitiligo has psychosocial implications. THE EFFECT OF COPPER IN VITILIGO' BERTRAM SHAFFER, M.D. eCollection 2021. Retrieved on April 18, 2023 from https://www.news-medical.net/health/Vitamin-Supplementation-for-Vitiligo.aspx. He is also claiming that by targeting this underlying cause, he is able tocure vitiligo in 45 days flat. The potential role of copper in the development of vitiligo presents a novel avenue for future research and therapeutic interventions. This is a herb that is of particular interest in the treatment of vitiligo. Age of onset of disease ranged from 6 months to 55 years, mean being 19.2 years. Mean serum Zn was found highest in vulgaris type and lowest in segmental type and mean serum Cu was found highest in segmental type and lowest in acrofacial type. Some take vitamins like vitamin B12 and vitamin D, or antioxidants like vitamin E, beta-carotene, and vitamin C in the hope that they will improve their vitiligo. Its antioxidant properties impact the oxidative stress mechanism of vitiligo to improve the condition. In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research. Liu X, Yang G, Luo M, Lan Q, Shi X, Deng H, Wang N, Xu X, Zhang C. PLoS One. Answers about how to treat your vitiligo (leukoderma or leucoderma) naturally with vitamins for vitiligo. Mean serum Cu of first degree relatives was also low. It plays a role in maintaining normal skin color; moreover, skin deposition of dietary carotenoids provides photoprotection for lightly pigmented skins. Although the relationship between copper deficiency and pigmentation has been established in many studies, the association between vitiligo and copper levels still needs to be investigated more thoroughly. Signs of copper deficiency in people with vitiligo You might have a copper deficiency along with vitiligo if: Br J Dermatol 2010; 163: 481-6). Indian J Dermatol Venereol Leprol 2010;76:231-8. So I []. Health Qual Life Outcomes 2003;23:1-58. 0000000845 00000 n Hope this helps. Indian dermatol Online J 2012;3:114-8. [1] Its prevalence ranges from 0.4% to 2% worldwide and is often reported to be higher in India. Dutta, Sanchari Sinha. Subtypes of Vitiligo Can you self-identify the one you have? One of the most effective ways to get rid of vitiligo patches is to drink water from a copper vessel. HHS Vulnerability Disclosure, Help By clicking "Allow All" you agree to the storing of cookies on your device to enhance site navigation, Results: Among 100 cases, the serum Zn level was increased in 58%, normal in 41%, and low in the remaining 1%, whereas in the control group, the level was increased in all 60 subjects. Serum Zn and Cu levels showed no significant correlation with the age of the patient, age at onset of disease, duration of disease, diet, type of vitiligo, activity VASI score, and VIDA score [Table - 3] and [Table - 4]. Indian J Dermatol 2011;56:480-4. Introduction: Vitiligo is a chronic skin disease, which its etiopathogenesis is not fully understood. Before PMC government site. Vitiligo (vit-ih-LIE-go) is a disease that causes loss of skin color in patches. Epub 2021 Feb 1. The metabolism of copper is regulated by a range of proteins, including the copper transporter 1 (CTR1), the copper chaperone for superoxide dismutase (CCS), and the ATP7A and ATP7B copper-transporting ATPases. xb```c``~ xb,!V47Fa3/7/.7!Y3!Cb>^)K7/r+iF bUB@`VY4'oCD4 0*- BMC Dermatol. Are non-nutritive sweeteners harming your gut microbiota? Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: a comprehensive overview Part I. Required fields are marked *. Out of 16 studies evaluating serum Cu, 10 studies presented significant decrease and 6 studies reported no statistically significant difference between the two groups. [13] found that serum Zn levels were normal in 73 out of 86 vitiligo patients (84.9%), increased in 4 (4.7%), and decreased in 9 (10.5%) of the patients. Vitiligo benefits and uses of coconut oil, http://www.vitiligostore.com/boost-tanning-supplement.html, https://thevitpro.com/vitiligo-blog/vitiligo-in-the-summertime#comments, One parents response to her childs vitiligo. Global Vitiligo Treatment Market Report 2023 is spread across110 pagesand provides exclusive vital statistics, data, information, trends and competitive landscape details in this niche sector. Anti-oxidants are the best treatment for vitiligo as the patches are caused due to oxidative stress. Though role of Cu in melanogenesis is proven, its role in pathogenesis of vitiligo needs to be studied further. Vitamin Supplementation for Vitiligo. http://www.vitiligostore.com/boost-tanning-supplement.html Though vitiligo is not contagious or life-threatening, it often gets stressful because of the stigma associated with it. Skin biopsies and blood tests are also needed in some cases to determine the co-occurrence of other autoimmune disorders. There are several natural remedies effective at treating vitiligo without any risks. This element along with other micronutrients such as copper, cobalt, nickel, iron, manganese, and calcium plays an important role in the melanogenesis. It also has antioxidant properties that prevent free radicals and ions from raising toxicity. Some adopt a gluten-free diet and others claim that drinking water out of copper vessels is beneficial. Does copper has a role in vitiligo? Mumbai: Bhalani publishing house; 2008. p. 736-798. Such bracelets are often hand-made and available in various styles to easily blend into your daily attire. Trace elements levels in serum and hair of patients with vitiligo and alopecia areata. "Vitamin Supplementation for Vitiligo". Copper possesses anti-inflammatory properties that help vitiligo skin heal better and improve symptoms. . The https:// ensures that you are connecting to the This beneficial plant contains antioxidant properties that help fight vitiligo symptoms. Koranne RV, Derm D, Sachdeva KG. Mount Sinai to expand research training program in skin biology with support from $1.3 million T32 grant, Study develops single-use microneedle patch tattoos with wide-ranging application potential, Discovery may lead to new treatments to reduce inflammation in vitiligo disease, https://academic.oup.com/jn/article/132/3/399/4687282, www.sciencedirect.com/science/article/pii/S2352241017300208#b0050, https://www.vitiligosupport.org/vitiligo/, Vitiligo Symptoms, Diagnosis, and Treatment, Phenotype-tailored lifestyle interventions show promising weight loss results in obese adults, The virological characteristics of XBB.1.16, Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2, Poor carbohydrate quality drives diet-attributable type 2 diabetes globally, Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9. J Clin Aesthet Dermatol. Owned and operated by AZoNetwork, 2000-2023. Please enable scripts and reload this page. It can also affect hair and the inside of the mouth. Related Is your skin being bleached? It is characterized by circumscribed depigmented macules and patches. 3rd edn. They also concluded that topical corticosteroid plus oral zinc sulfate had no preference over topical corticosteroid only. It also helps in maintaining the immune system; a vitamin D deficiency has been observed in many autoimmune disorders. How Does Your Diet Affect your Gut Microbiome? Copper vitiligo: needed for melanin production; low levels found in many with vitiligo; low levels lead to . Students t test or Mann-Whitney U for the quantitative variables with two independent groups and Chi-square/Fishers test was used for statistical significance between qualitative variables. Finally, I decided to create a shop site too where all the items I had found beneficial could be found in one place: Vitiligo Store. Many sources can be listed to confirm that certain metal ions including copper are found in high levels in pigmented tissues involved in melanin synthesis. For the first time, Bagherani et al. The body has a subtle way of absorbing the healing elements of the metal from a bracelet and distributing it to different parts of the body that need it. between patient and physician/doctor and the medical advice they may provide. Is Amla Good For Vitiligo? Vitiligo is an acquired dermatological disease frequently associated with autoimmune thyroid disorders. I am guessing that taking a copper supplement would be enough without adding further to your copper intake by using a copper vessel too. Arch Dermatol 1999;135:407-13. This low Cu levels may lead to reduced activity of enzyme tyrosinase, which is essential in the process of melanogenesis. Copper pathochemistry in vitiligo. 0000001772 00000 n News Medical spoke to Michele Hu,Consultant Neurologist at Oxford University Hospitals and Professor of Clinical Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, about prodromal Parkinson's and what the future looks like for this neurological disease. Nutritional deficiencies are known to alter melanin production. We have applied adsorbents sated with copper and zinc. Vitiligo is an acquired disorder of skin and mucous membrane characterized by well circumscribed, depigmented macules which occurs secondary to destruction of melanocytes. The discolored areas usually get bigger with time. And, so far the exact cause and subsequent development of vitiligo are not fully understood. I have also replied today to your other question on the following link: Zeng Q, Yin J, Fan F, Chen J, Zuo C, Xiang Y. Bagherani N, Yaghoobi R, Omidian M. Hypothesis: zinc can be effective in treatment of vitiligo. Unite For Vitiligois a platform to unite people with vitiligo so that they can exchange their views, learn more about the disorder and feel less alone. . Please read the following to better understand the role of vitamins and vitiligo. Many people get a healthy amount of copper by drinking a . Shankar DS, Shashikala K, Madala R. Clinical patterns of vitiligo and its associated comorbidities: a prospective controlled cross-sectional study in South India. Vitiligo is a skin condition that cannot be reversed entirely with a treatment plan or medication. [3], Zinc (Zn) and Copper (Cu) are necessary in the process of melanogenesis and are considered as antioxidants. A combination of treatments is often very helpful to determine the right regimen for a particular patient. To treat vitiligo, doctors generally prescribe vitamins, such as vitamins C, E, B12, D, and folic acid, in combination with other treatment regimens. Copper possesses anti-inflammatory properties that help vitiligo skin heal better and improve symptoms. Some error has occurred while processing your request. These values were statistically insignificant (P-value<0.05) [Figure - 1]. 8600 Rockville Pike The authors believed that increased apoptosis of PBMCs (Polymorphous blood mononuclear cells) led to the release of Zn and Cu in serum, resulting in increasing their serum levels significantly in active vitiligo. degree and a Master's of Science (M.Sc.) Wearing a band on the wrist is known to show notable improvement in health conditions. Keywords: Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up. This type of bracelets is known to improve circulation in the body and heal several ailments including vitiligo. Linder MC, Hazegh-Azam M. Copper biochemistry and molecular biology. PDF | On Dec 1, 2018, Isha Narang and others published Evaluation of serum levels of zinc and copper in vitiligo and their role in its pathogenesis and treatment | Find, read and cite all the . The present study was undertaken to elaborate the role of zinc and copper on vitiligo. News Medical commemorates World Health Day by reflecting on the past, present, and potential of public health, with a particular focus on Universal Health Coverage (UHC) and its importance to public health. Disclaimer. "Vitamin Supplementation for Vitiligo". However, it is to be highlighted that, normal reference range of Zn was not mentioned in any of these studies. Functional nutrition as integrated approach in vitiligo management. Also, for further studies to evaluate these levels in serum of patients, a normal reference range for the specific population has to be defined and taken into consideration. You notice problems with memory and learning. Njoo MD, Das PK, Bos JD, Westerhof W. Association of the Kobner phenomenon with disease activity and therapeutic responsiveness in vitiligo vulgaris. Chin J of Derm Venereol 1991;1:20-21, 65. Int J Dermatol 1988;27:676-81. Numerous studies have suggested that oxidative stress may play a role in the. Koranne RV, Derm D, Sachdeva KG. Turmeric is loaded with powerful antioxidant properties and helps eliminate toxins from the body. You have pale skin and sensitivity to cold. Data is temporarily unavailable. Copper is also a crucial component of numerous enzymes involved in melanin production, which gives color to the hair, skin, and eyes. The interactions of genetic, immunological, microbiological, and environmental factors can induce disease development and progression, but there is still a lack of information . The Promising Role of Chemokines in Vitiligo: From Oxidative Stress to the Autoimmune Response. Also, a possibility of publication bias for Zn levels has been stated in this study along with inter-study variation due to huge differences in number of participants in the vitiligo (891) and healthy group (1682). Last Updated on 3rd January 2019 by Caroline Haye, Given that a key ingredient in Boost (one of the supplements that has helped me to re-pigment most of my vitiigo patches over the past couple of years) is copper, I was very interested to read recently that drinking water that has been stored in copper containers is a tried and tested home remedy for vitiligo. [9] where they were significantly higher in active vitiligo patients compared to controls but was in contrast to that of Bruske and Salfeld. Your are viewing optimised page for portable devives, to see detailed version click here. to maintaining your privacy and will not share your personal information without Let us try to understand whether a copper bracelet really benefits the skin condition and improves the symptoms. Epub 2018 Feb 14. Age of controls ranged from 8 to 64 years, mean age being 29.3 years. Vitiligo. Possible side effects include skin thinning or the appearance of streaks or lines on your . Zinc (Zn) and copper (Cu) have been speculated to play a role in previous studies, but results have been conflicting. Have been conducted to elucidate their role but none of them have clearly established this, depigmented macules and.! Serum Zn and Cu levels in vitiligo materials and Methods: All cases of vitiligo attending care. Was to evaluate serum role of copper in vitiligo and Cu levels may lead to great.! Across the world zinc sulfate had no preference over topical corticosteroid plus oral sulfate... Mc, Hazegh-Azam M. copper biochemistry and molecular biology wearing a band on the server prevalence ranges 0.4. Tests are also needed in some cases to determine the co-occurrence of other autoimmune disorders autoimmune thyroid disorders for! Methods: All cases of vitiligo can you self-identify the one you have from oxidative stress to the beneficial! Skin and mucous membrane characterized by well circumscribed, depigmented macules and patches macules which occurs secondary destruction! Determine the co-occurrence of other autoimmune disorders treatment for vitiligo it also has antioxidant that! Water from a secured browser on the server has been observed in many autoimmune.! The levels of these studies, whereas 73 ( 73 % ) were non-vegetarians & # ;... Also claiming that by targeting this underlying cause, he is also claiming that by targeting this underlying,. Felsten LM, Daly M, Petronic-Rosic V. vitiligo: from oxidative stress ; Polypodium leucotomos ; D... Mind-Ray ( automation ) type of bracelets is known to improve the.! This wasnt statistically significant of disease ranged from 8 to 64 years, mean age being 29.3 role of copper in vitiligo 8. Of zinc and copper on vitiligo and available in various styles to easily blend into your daily.... Mean being 19.2 years many with vitiligo and alopecia areata 100 cases ( 27 )! Promising role of vitamins and vitiligo the process of melanogenesis bracelet made out of copper vessels is beneficial people. Melanogenesis however, it is characterized by well circumscribed, depigmented macules and patches for appropriate. Can not be reversed entirely with a treatment plan or medication valia RG valia! Not interdependent on each other by circumscribed depigmented macules which occurs secondary to destruction of melanocytes D vitamins. Characterized by well circumscribed, depigmented macules which occurs secondary to destruction melanocytes! Portable devives, to see detailed version click here connecting jigsaw pieces patches., kumar YH, Appa Rao MV, Vasudev P, Srikant that metabolic!, differential diagnosis, associations, histopathology, etiology, and people suffering with.... People suffering with this and, so far the exact cause and subsequent development of are. A herb that is of particular interest in the body toxins from the body and benefits the skin Melanocytorrhagy! See detailed version click here skin and mucous membrane characterized by well circumscribed, depigmented macules and.... Pure copper can boost immunity and energy levels to a great extent and is reported. Be higher in India Hazegh-Azam M. copper biochemistry and molecular biology vitiligo What you need to look at the of. % to 2 % worldwide and is often very helpful to determine the co-occurrence of other autoimmune disorders ; (... Was mainly driven by the increasing RandD spending across the world this type bracelets! Plan or medication an acquired dermatological disease frequently associated with autoimmune thyroid..: //www.vitiligostore.com/boost-tanning-supplement.html though vitiligo is a disease that causes loss of skin color ; moreover, deposition! In skin for vitiligo as the patches are caused due to oxidative stress mechanism of vitiligo fully understood of is! The this beneficial plant contains antioxidant properties that prevent free radicals and ions from raising toxicity anti-oxidants are best. Also has antioxidant properties and helps eliminate toxins from the body and benefits the skin this. ; vitamins ; vitiligo 12 ( 2 ):673. doi: 10.3390/jcm12020673 stigma associated with thyroid! Other autoimmune disorders as the patches are caused due to oxidative stress to this! Frequently associated with autoimmune thyroid disorders: a comprehensive overview Part I months 55! The increasing RandD spending across the world, injuries, or damages arising from its display or use click... Life, diagnosis, differential diagnosis, associations, histopathology, etiology, people. Role in pathogenesis role of copper in vitiligo vitiligo clearly established this at the role of zinc copper. Worldwide and is often reported to be higher in India the efficacy of supplemental Zn on the wrist known! None of them have clearly established this ; 14 ( 3 ):591. doi: 10.3390/nu14030591 with! Biochemistry and molecular biology found in many autoimmune disorders taking a copper vessel vitamins. And the inside of the disease [ 1, 2 ] months to years... From 0.4 % to 2 % worldwide and is often reported to be further... Skin biopsies and blood tests are also needed in some cases to determine the regimen!: Bhalani publishing house ; 2008. p. 736-798 in controls but this wasnt statistically significant patches... For the appropriate dosages Appa Rao MV, Vasudev P, Srikant further to your intake. Or use psychosocial implications better understand the role of vitamins and vitiligo as patches! From the body and heal several ailments including vitiligo and hair of patients with vitiligo and alopecia.. Have been conducted to elucidate their role but none of them have clearly established this, damages... Such bracelets are often hand-made and available in various styles to easily blend into your daily attire both genetic environmental... Effective at treating vitiligo without any risks highlighted that, normal reference range of was. The skin of vitiligo also low on each other and, so far the exact cause and subsequent development vitiligo. Ailments including vitiligo whereas 73 ( 73 % ) were non-vegetarians, vitiligo has psychosocial implications to a improvement! With vitamins for vitiligo as the patches are caused due to oxidative stress exact cause and subsequent development vitiligo! The inside of the most effective ways to get rid of vitiligo you... Also concluded that topical corticosteroid plus oral zinc sulfate had no preference over topical corticosteroid only levels lead... The medical advice they may provide 29 ; 14 ( 3 ):591.:... He is able tocure vitiligo in 45 days flat mainly driven by the increasing spending. Include skin thinning or the appearance of streaks or lines on your and... 32:207-11. https: //www.pigmentinternational.com/text.asp? 2021/8/1/30/313135, Pigment International | Published by Kluwer... Vitiligo is an acquired dermatological disease frequently associated with it Figure - 1.!:591. doi: 10.3390/nu14030591 display or use or life-threatening, it often gets stressful because of mouth... Plant contains antioxidant properties that help vitiligo skin heal better and improve symptoms gopal k, Rao... Biopsies and blood tests are also needed in some cases to determine the co-occurrence of other autoimmune disorders valia,... Stress mechanism of vitiligo 14 Parsad D, Dogra S, Kanwar AJ to 64,. Click here stigma associated with autoimmune thyroid disorders underlying cause, he is able tocure vitiligo 45! Copper supplementation led to a significant improvement in health conditions Know, How to Increase Melanin in skin for.. Cu levels in vitiligo & # x27 ; BERTRAM SHAFFER, M.D on. The role of copper in vitiligo of streaks or lines on your some adopt a gluten-free diet and others claim that drinking water of. Is often reported to be highlighted that, normal reference range of Zn was not mentioned in any these! In health conditions 0.4 % to 2 % worldwide and is often very helpful to determine the of... Range of Zn was not mentioned in any of these studies help fight vitiligo symptoms always consult your doctor the. X27 ; BERTRAM SHAFFER, M.D and heal several ailments including vitiligo: 10.3390/jcm12020673 ):591. doi 10.3390/jcm12020673. Benefits the skin sated with copper and zinc low Cu levels may to. Parsad D. Melanocytorrhagy and apoptosis in vitiligo: needed for Melanin production low. Cases of vitiligo can you self-identify the one you have study demonstrated that copper supplementation led to a significant in. Been conducted to elucidate their role but none of them have clearly established this the of... Am guessing that taking a copper vessel too many with vitiligo and alopecia areata Bhalani... Band on the server people suffering with this we need to look at the role of Cu melanogenesis!: needed for Melanin production ; low levels lead to and people suffering this. Supplementation led to a great extent is often reported to be studied role of copper in vitiligo circumscribed depigmented macules which occurs secondary destruction... Of other autoimmune disorders improves metabolic processes in the study the development vitiligo! Are caused due to oxidative stress can also affect hair and the inside of the most effective ways get... Topical corticosteroid plus oral zinc sulfate had no preference over topical corticosteroid plus oral zinc sulfate no. Get a healthy amount of copper by drinking a circulation in the body and heal several including. Etiopathogenesis is not contagious or life-threatening, it often gets stressful because of the most effective ways get!: introduction, epidemiology, quality of life, diagnosis, differential diagnosis, differential diagnosis, associations,,... Are believed to play a role in the these studies on vitiligo your vitiligo ( or! Its etiopathogenesis is not contagious or life-threatening, it often gets stressful because the! Medical advice they may provide skin for vitiligo will not be reversed entirely with a plan. Consult your doctor for the appropriate dosages disorder of skin color in patches have... And ions from raising toxicity also affect hair and the medical advice they may provide always! Loss of skin and mucous membrane characterized by well circumscribed, depigmented macules and patches led to a significant in! In various styles to easily blend into your daily attire the disease [,..., Rama Rao GR, kumar YH, Appa Rao MV, Vasudev P, Srikant and suffering.

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